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Table 4 Baseline characteristics of cases (transmission strains) and controls (chronic strains)

From: Application of a case–control study design to investigate genotypic signatures of HIV-1 transmission

Characteristics Transmission Strains Chronic Controls
  (n = 133) (n = 133)
Subtype, n (%)   
B 78 (58.7) 78 (58.7)
C 55 (41.4) 55 (41.4)
α4β7 Binding Site, n (%)   
LDV 44 (33.1) 56 (42.1)
LDI 48 (36.1) 36 (27.1)
Both 92 (69.2) 94 (70.1)
Contains the ‘D’ 133 (100) 131 (98.5)
Histidine at position 12, n (%)   
  61 (45.9) 59 (44.4)
Histidine or Arginine at position 12, n (%)
  71 (53.4) 69 (51.9)
Amino Acid Length, V1 loop   
Range 9 to 48 15 to 45
Mean (standard deviation) 25.5 (6.12) 26.8 (6.40)
Amino Acid Length, V2 loop   
Range 33 to 52 33 to 59
Mean (standard deviation) 37.9 (3.37) 38.0 (3.69)
Amino Acid Length, V3 loop   
Range 27 to 28 26 to 31
Mean (standard deviation) 27.8 (0.41) 27.9 (0.50)
Amino Acid Length, V4 loop   
Range 6 to 30 2 to 27
Mean (standard deviation) 18.2 (4.40) 18.0 (4.13)