Table 4 Baseline characteristics of cases (transmission strains) and controls (chronic strains)
From: Application of a case–control study design to investigate genotypic signatures of HIV-1 transmission
Characteristics | Transmission Strains | Chronic Controls |
|---|---|---|
(n = 133) | (n = 133) | |
Subtype, n (%) | ||
B | 78 (58.7) | 78 (58.7) |
C | 55 (41.4) | 55 (41.4) |
α4β7 Binding Site, n (%) | ||
LDV | 44 (33.1) | 56 (42.1) |
LDI | 48 (36.1) | 36 (27.1) |
Both | 92 (69.2) | 94 (70.1) |
Contains the ‘D’ | 133 (100) | 131 (98.5) |
Histidine at position 12, n (%) | ||
61 (45.9) | 59 (44.4) | |
Histidine or Arginine at position 12, n (%) | ||
71 (53.4) | 69 (51.9) | |
Amino Acid Length, V1 loop | ||
Range | 9 to 48 | 15 to 45 |
Mean (standard deviation) | 25.5 (6.12) | 26.8 (6.40) |
Amino Acid Length, V2 loop | ||
Range | 33 to 52 | 33 to 59 |
Mean (standard deviation) | 37.9 (3.37) | 38.0 (3.69) |
Amino Acid Length, V3 loop | ||
Range | 27 to 28 | 26 to 31 |
Mean (standard deviation) | 27.8 (0.41) | 27.9 (0.50) |
Amino Acid Length, V4 loop | ||
Range | 6 to 30 | 2 to 27 |
Mean (standard deviation) | 18.2 (4.40) | 18.0 (4.13) |