Patient Identifier | Viral Loadb | Date Infected | ARTc |
|---|
D36 | Low | 1980 | Yes, 1999 |
C54 | Low | 1984 | No |
C98 | Low | 1982 | Yes, 1999 |
Patient 1 | BLD | Prior to 1983 | Yes, 1998 |
Patient SG1 | BLD | 1985 | No |
C49 | BLD | 1984 | No |
C64 | BLD | 1983 | No |
C135 | BLD | 1981 | No |
- a Patients reported to be infected by nef(−) HIV-1 for over fifteen years are presented with the appropriate identifier. D36, C54, C98, C49, C64, and C135 are from the Sydney Blood Bank Cohort [5, 50, 51]. Patient 1 was reported by Sullivan and co-workers [6, 36, 52]. Patient SG1 was reported by Benedetto and co-workers [9, 35]. bViral Load represented as “Low” indicates copies of viral RNA were generally found to be less than 10,000 copies/ml of peripheral blood but detectable. “BLD,” indicates viral load generally below the level of detection. D36, C54 and C98 had viral loads that were consistently detectable [50, 51]. Patient 1, Patient SG1, C49, C64, and C135 viral loads were not detectable [6, 35, 50]. The last four patients may have suppressed their HIV-1 infections by vigorous cytotoxic T cell responses [35, 51]. C54 did not appear to be progressing to AIDS at the time of death in 2001 [50]. cART is antiretroviral therapy.
