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Table 1 SHIV 162P3 env diversity in PrEP breakthroughs and untreated control macaques

From: Limited SHIV env diversification in macaques failing oral antiretroviral pre-exposure prophylaxis

 

Mean nucleotide diversity (%) (range)

 

PrEP

Controls

P value

Peak

0.027 (0.015-0.05)

0.053 (0.02-0.10)

P < 0.0001

Week 17*

0.14 (0.04-0.26)

0.53 (0.08-0.92)

P < 0.0001

  1. * Sequences were obtained an average of 17 weeks post peak viremia for the 4 PrEP breakthroughs (15, 16, 18, and 18 weeks) and the 5 untreated controls (12, 16, 18, 19, and 20 weeks).
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Retrovirology

ISSN: 1742-4690

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