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Figure 9 | Retrovirology

Figure 9

From: Second-site suppressors of HIV-1 capsid mutations: restoration of intracellular activities without correction of intrinsic capsid stability defects

Figure 9

The second-site mutation T216I restores the ability of P38A particles to saturate TRIM5 restrictions in simian cells. Cultures of OMK (A) and FRhK-4 (B) cells were inoculated with the indicated quantities of VSV-G-pseudotyped CA mutant HIV-1 particles and a fixed subsaturating quantity of GFP-encoding pseudotyped HIV-1 particles. Results shown are representative of two independent experiments.

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Retrovirology

ISSN: 1742-4690

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