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Table 1 Normalized activity of NC/p1 peptide cleavages by HIV protease

From: Modulation of HIV-1 Gag NC/p1 cleavage efficiency affects protease inhibitor resistance and viral replicative capacity

Virus

Peptide

Normalized activity (± SD)

Wild-type (HXB2)

ERQANFLGKIWPS

100 ± 5.0

436E + 437 T

ERQANFLGETWPS

240 ± 3.6

+435R

ERQANFLRETWPS

210 ± 18.9

+438R

ERQANFLGETRPS

160 ± 6.7