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Table 1 Characteristics of the three patients receiving an enfuvirtide-containing salvage therapy when samples were collected

From: The HR2 polymorphism N140I in the HIV-1 gp41 combined with the HR1 V38A mutation is associated with a less cytopathic phenotype

Patienta Sample Weeks on
ENF treatment
Plasma viral
load (copies/mL)
CD4+ cell
count (cells/μl)
No. of expression
plasmids constructed
140N (9) 140N 0 366357 491 5
  V38A 140N 24 8536 700 8
N140T (10) N140T 0 141497 13 10
  V38A N140T 4 332794 13 9
N140I (1) N140I 0 33470 145 10
  V38A N140I 12 10806 150 6
  1. aThe patient IDs from a previous work [29] are indicated in parentheses.