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Figure 1 | Retrovirology

Figure 1

From: HERV-H RNA is abundant in human embryonic stem cells and a precise marker for pluripotency

Figure 1

Schematic showing the strategy for detecting association between endogenous retro elements and the H3K4me3 marker. H3K4me3 CHiPSeq data for more than 40 different cell types were checked for association within 2 kB of all annotated endogenous retroviral elements (hg18) using methods described in reference [18]. Only HERV-H proviruses showed association with H3K4me3, and this was only significant in human ES cell lines. No association between H3K4me3 and endogenous retro-elements was detected in the mouse.

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