Figure 1
From: HERV-H RNA is abundant in human embryonic stem cells and a precise marker for pluripotency
Schematic showing the strategy for detecting association between endogenous retro elements and the H3K4me3 marker. H3K4me3 CHiPSeq data for more than 40 different cell types were checked for association within 2 kB of all annotated endogenous retroviral elements (hg18) using methods described in reference [18]. Only HERV-H proviruses showed association with H3K4me3, and this was only significant in human ES cell lines. No association between H3K4me3 and endogenous retro-elements was detected in the mouse.