Table 1 Inactivation of cell-free HIV-1 R5 and X4 strains by 2DLT
HIV-1 strain (subtype, tropism) | EC50 (nM) | |||
|---|---|---|---|---|
D1D2 | 2DLT | T1144 | T20 | |
Bal (B, R5) | 157.2 ± 34.2 | 24.5 ± 2.25 | >500 | >500 |
IIIB (B, X4) | 51.2 ± 9.21 | 17.3 ± 1.62 | >250 | >250 |
92US657 (B, R5) | 319.2 ± 56.1 | 48.7 ± 14.5 | >500 | >500 |
93 MW959 (C, R5) | 478.2 ± 89.3 | 78.6 ± 7.04 | >500 | >500 |
92TH009 (E/A, R5) | 209.5 ± 6.1 | 69.9 ± 14.4 | >500 | >500 |