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Table 1 GNB3 C825T genotype frequency for HIV-1 negative and HIV-1 positive individuals in the CSW cohort

From: The role of G protein gene GNB3 C825TPolymorphism in HIV-1 acquisition, progression and immune activation

GNB3 825 Genotype

HIV-1 Negative (n = 349)

HIV-1 Positive (n = 682)

CC (homozygous wildtype)

15 (4.3%)

27 (4.0%)

CT (heterozygous)

124 (35.5%)

206 (30.2%)

TT (homozygous variant)

210 (60.2%)

449 (65.8%)

CT Frequency

0.355

0.302

P for HWE

0.904

0.942

C allele

T allele

0.22

0.78

0.19

0.81

  1. Note: Data are no. (%) of subjects, unless otherwise indicated. For the comparison between HIV-1-negative and HIV-1-positive subjects, p = 0.19 (chi squared test). HWE, Hardy-Weinberg equilibrium