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Figure 2 | Retrovirology

Figure 2

From: Escape is a more common mechanism than avidity reduction for evasion of CD8+ T cell responses in primary human immunodeficiency virus type 1 infection

Figure 2

T cell responses to variant epitope peptides emerge during the first year following presentation with HIV infection. For 9 epitopes in 8 patients, PBMC from selected time-points during the first year following presentation with HIV infection were titrated against index sequence and variant sequence peptide(s) in an IFNγ ELISPOT assay. The concentration of index sequence peptide stimulating the maximal IFNγ response in the assay was determined. At each longitudinal time-point, the response to this concentration of the variant peptide(s) (black diamonds or grey squares) is shown, expressed as a percentage of the response to the index sequence peptide at the same peptide concentration.

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Retrovirology

ISSN: 1742-4690

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