Skip to main content
Figure 2 | Retrovirology

Figure 2

From: Mutagenesis of tyrosine and di-leucine motifs in the HIV-1 envelope cytoplasmic domain results in a loss of Env-mediated fusion and infectivity

Figure 2

Biosynthesis and processing of mutant glycoproteins. COS-1 cells transiently transfected with the Env expression vector pSRHS were metabolically labeled in a pulse, followed by a 4 h chase and immunoprecipitated with anti-HIV-1 patient sera. The locations of the Env precursor and the components of the mature Env complex are indicated at the left of the gel. The pulse-chase cell lysates of glycoproteins expressed from the pSRHS vector (A) are shown in the gel at the top, and the corresponding gel for the amount of gp120 shed into the supernatant (B), is shown in the gel at the bottom.

Back to article page

Retrovirology

ISSN: 1742-4690

Contact us