Figure 3
From: Tat RNA silencing suppressor activity contributes to perturbation of lymphocyte miRNA by HIV-1
Ablation of Tat RSS alters miRNA expression trends relative to HIV-1 and Vif-/Vpr-deficient HIV-1. Scatterplot analysis of miRNA mature and precursor probes expression changes observed on microarrays hybridized with RNA from human CEMx174 lymphocytes infected with HIV-1, ΔVV, or RSS. Log2 expression values of human miRNA probes in the HIV-1 infections are shown on the y-axis, log2 expression values for miRNA probes in either RSS or ΔVV infection are shown on the x-axis. (a) HIV-1 versus ΔVV infection; (b) HIV-1 versus RSS infection.