From: Antiviral activity of α-helical stapled peptides designed from the HIV-1 capsid dimerization domain
CI/μM | Kdiss/μM | ΔHdiss/kcal mole-1 | 200 μM CTD (fm)* |
---|---|---|---|
0 | 15.3 (±3.6) | 10.7 (±0.7) | 18% |
50 | 31.2 (±6.6) | 9.1 (±0.3) | 24% |
200 | 33.2 (±3.9) | 10.8 (±0.2) | 25% |
350 | 40.5 (±6.2) | 10.9 (±0.2) | 27% |