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Table 2 Frequencies of CCR2-CCR5 polymorphisms among HIV-1 serodiscordant couples, index partners, and HIV-1 exposed seronegative partners

From: Association of chemokine receptor gene (CCR2-CCR5) haplotypes with acquisition and control of HIV-1 infection in Zambians

   

HESNa partners

 

All (N = 1134)

Index partners (N = 567)

All (N = 567)

Seroconverters (N = 240)

Uninfected (N = 327)

Haplotype

N (%)

N (%)

N (%)

N (%)

N (%)

HHA

601 (26.5)

305 (26.9)

296 (26.1)

133 (27.7)

163 (24.9)

HHB

44 (1.9)

25 (2.2)

19 (1.7)

8 (1.7)

11 (1.7)

HHC

178 (7.9)

69 (6.1)

109 (9.6)

42 (8.8)

67 (10.2)

HHD

370 (16.3

190 (16.8)

180 (15.9)

75 (15.6)

105 (16.1)

HHE

310 (13.7)

138 (12.2)

172 (15.2)

61 (12.7)

111 (17.0)

HHF*1

128 (5.6)

76 (6.7)

52 (4.6)

24 (5.0)

28 (4.3)

HHF*2

480 (21.2)

259 (22.8)

221 (19.5)

99 (20.6)

122 (18.7)

HHG*1

157 (6.9)

72 (6.4)

85 (7.5)

38 (7.9)

47 (7.2)

HWE:Pb

0.0001

0.0001

0.267

0.024

0.160

  1. a HESN = HIV-1 exposed seronegative
  2. b P values for tests of Hardy-Weinberg equilibrium in each of the patient groups.