Notwithstanding a cumbersome anti-HIV management, the immune-virological situation remained under control (the last laboratory assays showed a viremia of 1,300 HIV-RNA copies/mL, and a CD4+ count of 612 cells/μL), and our p never suffered from AIDS-related complications. Unfortunately, starting 7 years ago, a bilateral symmetric lipomastia appeared, associated in the past two years with a bilateral, dorsal lipid accumulation (both confirmed by ultrasonography), which were responsible for severe psychological disturbances. Hormonal-metabolic workup failed in disclosing relevant abnormalities, as to serum FSH, LH, testosteron, estradiol, estrone, progesteron, dehydroepiandrosterone, and prolactin levels, thyroideal profile (TSH, fT3, fT4, and anti-thyroid antibodies), as well as metabolic pattern (fasting glucose, total cholesterolemia, HDL- and LDL- fractions, apolipoproteins, C-peptide, insulin, fruttosamin, glycosilated hemoglobin, lactate, and bicarbonate), when excluding a moderate hypertriglyceridemia.