Background
It is known that the circulating Vdelta2 T cell subset respond to mycobacteria and certain viruses, while the Vdelta1 subset is resident in the mucosal-asssociated lymphoid tissue and participate in the immunity against intracellular microrganisms. We reported that in HIV-1 infected patients circulating Vdelta1 T lymphocytes are increased; in vitro, these cells can proliferate in response to Candida albicans. We analysed the effects of influenza virus vaccination on the function of this T cell subset in HIV-1 infected patients and healthy donors.