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Figure 9 | Retrovirology

Figure 9

From: Misfolding of CasBrE SU is reversed by interactions with 4070A Env: implications for gammaretroviral neuropathogenesis

Figure 9

Assessment of CasBrE Env binding to mCAT-1 by superinfection interference. Control, CasES- and CasE-C17.2 NSCs with and without 4070A infection were subjected to infection by the ecotropic virus, Fr57E, to assess the ability of NSCs-expressing CasBrE Env or SU to block Fr57E entry through the ecotropic virus receptor mCAT-1. Viral foci on NSCs were detected with monoclonal antibodies 48, 500, and 720 that are specific for the Friend virus Env [38, 39]. Error bars represent the standard deviation of the log of the Fr57E virus titers. N = 4 for all the samples.

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