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Figure 7 | Retrovirology

Figure 7

From: Analysis of infectious virus clones from two HIV-1 superinfection cases suggests that the primary strains have lower fitness

Figure 7

Transcriptional activity of the LTR promoter sequences. Transcriptional activity of the HIV-1 LTR promoter sequences from HIV strains B(LAI), B1, B2, B3, and B4, compared with the empty vector (pGL3-basic) in a dual firefly/renilla luciferase assay. LTR fragments cloned from clones B1.1/B1.3 and B4.2/B4.4 are identical in sequence, so only strain names are indicated. Transcriptional activity of the luciferase gene was tested in the presence of increasing concentrations of Tat. The value is the average of three independent measurements; standard deviations are indicated.

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