Figure 5

Structure of the LTR polyA hairpin. Predicted structure of the LTR polyA hairpin region of the HIV-1 reference strain HXB2 and clones B3.1, B4.2 and B4.4. The free energies of the stem-loop structures were calculated with the Zuker algorithm as available at the mfold webserver for nucleic acid folding and hybridization prediction [69], the ΔG values are presented in kilocalories per mole. A box indicates the UU→CA change in clone B3.1.