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Open Access

Small RNA-mediated control of retrotrotransposons in Drosophila

  • Severine Chambeyron1,
  • Christine Brun1,
  • Alain Bucheton1,
  • Alain Pélisson1 and
  • Vincent Serrano1
Retrovirology20096(Suppl 2):O5

Published: 24 September 2009


Infectious DiseaseCancer ResearchSomatic CellImportant VariationSmall RNAs

In the Drosophila ovary, the I-element (a NLR retrotransposon) and gypsy are both controlled by piRNAs (small RNAs associated with Piwi-like proteins); but there are important variations on this common theme, according to the cell lineage where it operates: the germline (for the I-element) versus the ovarian somatic cells (for gypsy). We are taking advantage of these differences to study the piRNA biogenesis, the epigenetic effects of the maternal transmission of piRNAs and the mechanism of piRNA-mediated regulation.

Authors’ Affiliations

IGH (CNRS), Montpellier, France


© Chambeyron et al; licensee BioMed Central Ltd. 2009

This article is published under license to BioMed Central Ltd.