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Novel cellular processes that regulate post-transcriptional expression of HIV-1 transcripts

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5'-capping is an early mRNA modification that has important consequences for downstream events in gene expression such as pre-mRNA synthesis and splicing, mRNA cytoplasmic transport, translation, and mRNA turnover. The role of RNA-capping in post-transcriptional regulation of HIV-1 expression has not been examined in detail. Here, we will present data on the roles played by cellular proteins and HIV-1 RNA capping on post-transcriptional expression of viral RNAs.

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Correspondence to Kuan-Teh Jeang.

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Open Access This article is published under license to BioMed Central Ltd. This is an Open Access article is distributed under the terms of the Creative Commons Attribution 2.0 International License (https://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Jeang, K. Novel cellular processes that regulate post-transcriptional expression of HIV-1 transcripts. Retrovirology 6, I15 (2009) doi:10.1186/1742-4690-6-S2-I15

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Keywords

  • Gene Expression
  • Infectious Disease
  • Cancer Research
  • Cellular Process
  • Viral RNAs