Figure 7

Nucleotide sequence of the HTLV-4(1863LE) LTR and pre- gag region. The U3-R-U5 locations (vertical lines), the pre-B cell leukemia (Pbx-1, TGACAG) and c-Myb (YAACKG) transcription factor binding sites, approximate cap site (cap), polyadenylation (poly(A)) signal, TATA box, predicted splice donor site (sd-LTR), and two 21-bp repeat elements (middle and proximal based on positions in HTLV-1 and -2), as well as the location of the distal 21-bp repeat in HTLV-1 and -2 (dashed lines), are indicated. In the R and U5 regions, the predicted Rex core elements and nuclear riboprotein A1 binding sites are underlined. The pre-gag region and primer binding site (PBS, underlined) are in italics.