Figure 2

Twenty-three association rules that include epitopes from three genes, and the respective amino acid sequences of the involved CTL epitopes (level of support >= 75%, confidence >= 95%), identified in 62 reference sequences of HIV-1 genomes (including 18 CRFs). Amino acid coordinates within each gene (Gag, Pol or Nef) are given relative to the epitope position in the HXB2 reference sequence (GenBank accession number K03455). Each line corresponds to a single association rule, and dashes designate amino acid sites that are NOT involved in the association rule. Drawn not to scale, "//" marks long stretches of non-included amino acid residues, and | indicates the border of a protein-coding gene. The numbers on the right side indicate the presence of the respective epitope association in other data sets: 1: 44-non-CRFs, 2: 18-CRFs and 3: Both 44-non-CRFs and 18-CRFs.