Figure 5

Tat interaction network. Here we mapped, using Osprey as a visualization tool, previously established interactions between the individual components of the Tat interaction dataset employing publicly available protein-protein interaction databases (BIND and HPRD) combined with extensive literature search. The network reconstruction of the Tat interactome revealed the higher-order and collective behaviour of the Tat interacting proteins, which compose large but well defined biochemical entities, represented by coloured circles. Edges represent interactions and individual proteins are depicted as nodes. Names in bold and red indicate the previously known Tat interactors and names in bold and blue represent proteins which identity was validated by WB analysis.