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Figure 2 | Retrovirology

Figure 2

From: The triple combination of tenofovir, emtricitabine and efavirenz shows synergistic anti-HIV-1 activity in vitro: a mechanism of action study

Figure 2

Synergistic inhibition of HIV-1 replication by combinations of (A) TFV+FTC, (B) TFV+EFV, and (C) FTC+EFV analyzed by MacSynegy II. Calculated additive antiviral interactions were subtracted from experimentally determined values to reveal regions and corresponding concentrations at which synergistic antiviral interactions occurred. Peaks of statistically significant (95% confidence level) synergy are shown in colors from dark blue to red, with red indicating the strongest synergy. Values used to describe the percentage of inhibition above the expected were derived from five experiments.

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Retrovirology

ISSN: 1742-4690

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