Wound induced bioluminescence in TAX-LUC mice. Surgical lesions were experimentally introduced in ear (A) limb (B), and tail tissue (C). The effect of adjuvant on wound associated bioluminescence was also examined (B, C). Treatments include 1) vehicle, 2) CFA, 3) wound, and 4) wound and CFA. Images were obtained 0.5 hrs before treatment, and 0.5, 2, 24, and 48 hrs after treatment. Representative images shown from A) 30 minutes, B) 2 hours, and C) 24 and 48 hours after treatment.