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Table 2 Analysis of inhibition of pseudotype infection in the presence of anti-CD4 antibody.

From: The V1-V3 region of a brain-derived HIV-1 envelope glycoprotein determines macrophage tropism, low CD4 dependence, increased fusogenicity and altered sensitivity to entry inhibitors

  BS Bv1v3 Bv1v2 Br (N283T) Spl SB Spl (T283N) DS17 DS17 (N283T)
Br 0.2363 0.8349 0.0032 0.3344 0.0005 0.0004 0.0027 <0.0001 <0.0001
BS   0.2286 0.0010 0.2638 <0.0001 <0.0001 <0.0001 <0.0001 <0.0001
Bv1v3    0.0021 0.5091 <0.0001 0.0001 0.0010 <0.0001 <0.0001
Bv1v2     0.0472 0.0212 0.1048 0.1863 0.0002 0.0001
Br(N283T)      0.0008 0.0013 0.0064 <0.0001 <0.0001
Spl       0.1783 0.1787 0.7203 0.8227
SB        0.8959 0.0055 0.0066
Spl(T283N)         0.0067 0.0023
DS17          0.1487
  1. Significance (p) values were obtained with an F test; p values below 0.05 were considered significant (shown in bold) an indicate rejection of the null hypothesis of a single best fit curve for both data sets.