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Table 1 Analysis of the relative pseudotype infection in cells expressing low levels of CD4.

From: The V1-V3 region of a brain-derived HIV-1 envelope glycoprotein determines macrophage tropism, low CD4 dependence, increased fusogenicity and altered sensitivity to entry inhibitors

 

BS

Bv1v3

Bv1v2

Br (N283T)

Spl

SB

Spl (T283N)

DS17

DS17 (N283T)

Br

0.670

0.462

0.019

0.831

0.019

0.020

0.021

0.394

0.394

BS

 

0.715

0.025

0.522

0.010

0.010

0.011

0.262

0.337

Bv1v3

  

0.144

0.584

0.018

0.049

0.027

0.465

0.715

Bv1v2

   

0.016

0.109

0.054

0.055

0.631

0.337

Br(N283T)

    

0.004

0.010

0.011

0.200

0.423

Spl

     

0.669

0.670

0.037

0.037

SB

      

0.767

0.087

0.054

Spl(T283N)

       

0.055

0.055

DS17

        

0.873

  1. Significance (p) values were obtained with the non-parametric Mann-Whitney test for the comparison of the relative infection with the indicated pseudotypes in cells expressing low levels of CD4; p values below 0.05 were considered significant (shown in bold).