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Table 1 Probability of monophyletic origin for L90M sequences

From: Multiple independent origins of a protease inhibitor resistance mutation in salvage therapy patients

Patient

p(monophyly)

Multiple origins L90M

608

0.05

6501

0.00

1125

0.00

1174

0.00

1317

0.00

Single origin L90M

1124

0.99

4334

1.00

Inconclusive

597

0.34

7071

0.29

1134

0.23

1329

0.14

1391

0.87

1527

0.30

1834

0.58

2091

0.18

  1. The probability that sequences containing the L90M mutation within each patient were derived from a single (p≥0.95) or multiple (p≤0.05) mutation events, given as the proportion of 9000 trees drawn from the posterior distribution of the Bayesian MCMC analysis in which the sequences with the L90M mutations formed a monophyletic clade.