Figure 7

Effects of anti-CD4 MoAb, the fMLF peptide, and RANTES on the susceptibility of cells to HIV/SIV strains. NP-2/CD4/CCR5 (open symbols) and NP-2/CD4/FPRL1 (closed symbols) cells were pretreated with anti-CD4 MoAb Nu-TH/I (A), the fMLF peptide (B) or RANTES for two hours at 37°C (C), and then inoculated with two HIV-1 strains, GUN-7WT (○ and ●) and HCM342 (□ and ■), HIV-2 CBL23 strain (△ and ▲), and SIV mndGB-1 strain (◇ and ◆). Six days after infection, cells positive for HIV-1 antigens were detected by IFA using a fluorescence microscope.