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Figure 3 | Retrovirology

Figure 3

From: Evolution of DC-SIGN use revealed by fitness studies of R5 HIV-1 variants emerging during AIDS progression

Figure 3

DC-SIGN use of R5 isolates in relation to PNGS in gp120 V2 (aa160) and V4 (aa406) regions. Figures display results from (a, d) binding assays, (b, e), trans-infections of PBMC and (c, f) trans-infections of C6 cells as target cells. Isolates were classified according to presence or absence of PNGS; open circles, isolates completely lacking PNGS; dark circles, isolates displaying PNGS in at least one of the clones sequenced. Presented data are the averages from results obtained in two or three assays performed. *p < 0.05; ** p < 0.01.

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