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Figure 1 | Retrovirology

Figure 1

From: Evolution of DC-SIGN use revealed by fitness studies of R5 HIV-1 variants emerging during AIDS progression

Figure 1

Ability of sequential R5 isolates to bind and utilize DC-SIGN for trans -infection. (A) DC-SIGN binding ability assessed as percentage specifically DC-SIGN associated p24 antigen. Efficiency of DC-SIGN mediated trans-infections analysed as ratios of p24 antigen release in DC-SIGN mediated PBMC (B) or T-cell line C6 (C) infections over p24 antigen release in directly infected PBMC and C6 cultures respectively. Presented data are average from results obtained in two or three assays performed. *, p < 0.05

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Retrovirology

ISSN: 1742-4690

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