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Table 2 Discriminatory antibodies for CD4+ T cellsa

From: Antibody microarray analysis of cell surface antigens on CD4+ and CD8+ T cells from HIV+ individuals correlates with disease stages

Discriminatory Antibody

Up(+)/Down(-)

P Value

BDL vs. NEG

  

CD11b

+

0.0599

CD95

+

0.0619

CD45RA

-

0.0679

LTNP vs. NEG

  

CD71

+

0.0151

CD 212 b1

+

0.0307

HLA-DR

+

0.0312

CD27 PH

-

0.0560

CD11b

+

0.0589

CD95

+

0.0752

VIR vs. NEG

  

CD71

+

0.0032

CD11b

+

0.0227

CD57

+

0.0307

CD95

+

0.0349

CD28

-

0.0540

CD218a

+

0.0732

CD86

+

0.0744

BDL vs. LTNP

  

CD183

-

0.0105

HLA-DR

-

0.0270

CD38

-

0.0316

CD71

-

0.0385

CD218a

-

0.0470

CD212 b1

-

0.0687

CD54

-

0.0695

VIR vs. LTNP

  

CD183

-

0.0451

CD3epsilon

-

0.0489

CD27 PH

+

0.0829

VIR vs. BDL

  

CD71

+

0.0195

CD218a

+

0.0355

CD54

+

0.0421

  1. aSix paired comparisons of CD markers on CD4+ cells providing significant discrimination between patient groups, with relative changes in CD antigen binding in the former vs. the latter denoted by "+" and "-" to indicate increase and decrease, respectively. Antigens that did not achieve statistical significance (p > 0.05) but have been previously reported in HIV disease context or have been found to be significant in other pair comparisons are also shown in italic. The "PH" in CD27 PH distinguishes this Pharmingen antibody (clone M-T271) from the Immunotech antibody 27 IM (clone 1A4-CD27).