Retroviral activation of the mir-106a microRNA cistron in T lymphoma

Retrovirology

Table 1 Assayed mmu-mir-106a cistron integrations

#	Tumor	Location	Orientation
1	1759S-158-18	chrX:48988832	G-T-
2	1890S-76-1	chrX:48988834	G-T+
3	718S-68-23	chrX:48989486	G-T+
4	1786S-166-32	chrX:48989857	G-T-
5	818S-36-8	chrX:48989770	G-T+
6	553S-122-16	chrX:48990068	G-T-
7	1758S-158-17	chrX:48989877	G-T+
8	1189S-187-12	chrX:48989980	G-T+
9	3390T-128-37	chrX:48990180	G-T-
10	3412S-171-29	chrX:48990192	G-T+
11	1544S-136-23	chrX:48990391	G-T-
12	49S-41-2	chrX:48991005	G-T-
13	800S-	chrX:48991024	G-T+
14	2061S-165-11	chrX:48991259	G-T-
15	462S-66C-20	chrX:48991159	G-T+
16	494S-95-4	chrX:48996521	G-T+
17	1469S-150-34	chrX:48999846	G-T+
18	195S-19-7	chrX:49000742	G-T+
19	463S-66-21	chrX:49002308	G-T+
20	1415S-	chrX:49004115	G-T+
21	2057S-172-23	chrX:49005225	G-T-

Retroviral insertion site locations (February 2006 version of the UCSC mm8 genome assembly) are noted by the basepair located just before the insertion. Orientation of the retrovirus is described using the following nomenclature. The gene transcript (G) and retroviral tag (T) is directly followed by a "+" for directionality of left to right or by a "-" for directionality of right to left on the chromosome. If the gene transcript is located to the left of the retroviral tag on the chromosome, the notation for the gene precedes the notation for the tag (G ± T±). If the transcript is to the right of the retroviral tag on the chromosome the order is reversed (T ± G±). If the tag is located within the gene, by default the gene precedes the tag annotation.

ISSN: 1742-4690