Figure 2

Testable predictions of the hypothesis. After a period of HIV infection (at Time X), there will be three outcomes for the distribution. If hA3G level has no effect on HIV disease progression, the distributions of hA3G level in HIV-infected and HIV-uninfected individuals should overlap (No effect, middle). If hA3G plays a protective role, its distribution in HIV-infected patients will shift to the right in comparison to that of HIV-uninfected controls (Protective, right). If hA3G plays a detrimental role, then its distribution in HIV-infected patients will shift to the left in comparison to HIV-uninfected individuals (Detrimental, left).