LAD-1 and LAD-1/variant T cells form smaller clusters with DC. (A) Representative light microscopic images of DC-T cell clusters with healthy, LAD-1 and LAD-1/variant T cells, one day after HIV-1 transmission. (B) The number and diameter of DC-T cell clusters of cells from LAD-1 patients (n = 3), the LAD-1/variant patient (n = 1), and healthy controls (n = 3) were determined one day after HIV-1 transmission, and the clusters were subsequently grouped according to size. Error bars represent standard deviations. *P < 0.05, **P < 0.01, compared to corresponding cluster group from 'control'.