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Figure 1 | Retrovirology

Figure 1

From: The conserved dileucine- and tyrosine-based motifs in MLV and MPMV envelope glycoproteins are both important to regulate a common Env intracellular trafficking

Figure 1

CD25-MLV and CD25-MPMV accumulate in the TGN. Forty-eight hours after transfection with the appropriate chimera cDNA, cells were treated with cycloheximide for 3 hours prior to fixation and staining. A. Co-staining of CD25 chimeras and Mannose 6-phosphate receptor of 46 kDa (MPR46), a protein that accumulates in the TGN at steady state. B. Co-staining of CD25 chimeras and internalized Cy3-conjugated tranferrin revealing the early/recycling endosomes. C. Co-staining of CD25 chimeras and Lamp1, a protein resident of the lysosomes.

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Retrovirology

ISSN: 1742-4690

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