Figure 2

Susceptibility of HIV-2_ROD Protease to Protease Inhibitors in transformed yeast 0.02 OD₆₀₀/well of BY4741 [pRS316Gal1/10-HIV2PR] cells were either incubated in Galactose (A) or Glucose (B) containing synthetic media in the presence of increasing amounts of LPV and SQV (from 1.5 μM to 200 μM) in a 96 well plate. After 48 h at 30°C cellular growth was determined by measuring cell density at 600nm and plotted against PI concentrations. Results are presented as the percentage of cell growth; [(OD₆₀₀ cells grew in Galactose with PI – OD₆₀₀ cells grew in Galactose)/OD₆₀₀cells grew in Glucose] × 100.