Figure 4
From: Transactivation of elements in the human endogenous retrovirus W family by viral infection
Expression of specific HERV-W elements following influenza A/WSN/33 infection. Levels of transcripts from the HERV-W gag on chromosomes 5p13, 11q13, 3q26 and the HERV-W env ORF encoding syncytin on 7q21 in CCF-STTG1, 293F and U937 cells infected with influenza A/WSN/33 (n = 3-7) relative to uninfected control cells (n = 3-9). Transcripts from 5p13 were not detectable in CCF-STTG1 or 293F cells in either control or infected cells, indicated by nd (not detectable). Syncytin transcripts were not detected in 293F control cells but were readily detectable (ct 34–35 using 500 ng input total RNA) in influenza A/WSN/33 infected cells, resulting in an infinite relative expression as indicated by ∞. Statistical significance is indicated by * = p < 0.05, ** = p < 0.01, *** = p < 0.001.