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Figure 4 | Retrovirology

Figure 4

From: Tumour necrosis factor-α stimulates HIV-1 replication in single-cycle infection of human term placental villi fragments in a time, viral dose and envelope dependent manner

Figure 4

Ex vivo bioluminescence imaging of HIV-1 infected placental chorionic villi stimulated or not with TNF-α. Placental chorionic villi were placed in contact with pseudotyped HIV-1 overnight. After the addition of luciferine for 4 h at 37°C, the tissues were analysed with the Xenogen system. Infection of chorionic villi with 2 ng of p24/fragment of VSV-G pseudotyped HIV-1 in the absence (well 1) or presence of 5 ng/ml of TNF-α (well 3). Infection of chorionic villi with 20 ng of p24/fragment of delta-Env pseudotyped HIV-1 in the absence (well 2) or presence of 5 ng/ml of TNF-α (well 4).

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Retrovirology

ISSN: 1742-4690

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