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Table 4 Ratio of nonsynonymous (dn) to synonymous (ds) substitutions in NC and p6 sequences from six HIV-1 infected mother-infant pairs involved in vertical transmission.

From: Molecular characterization of the HIV-1 gagnucleocapsid gene associated with vertical transmission

Pair

Mothers

Infants

 

N

p1

p2

p3

dn/ds

N

p1

p2

p3

dn/ds

B

13

0

0

100

1.37

11

0

100

0

1.00

C

9

0

0

100

1.51

15

11.72

86.09

2.19

22.84

D

17

0

99.02

0.98

68.79

12

87.26

0

12.74

6.75

E

11

83.68

0

16.32

33.75

12

48.04

51.02

0.94

37.57

F

18

0.03

0

99.97

1.20

15

21.48

77.20

1.32

9.00

H

16

0

100

0

89.00

-

-

-

-

-

I1H

-

-

-

-

-

11

100

0

0

21.24

I2H

-

-

-

-

-

8

68.65

0

31.34

5.47

Total

84

13.95

33.17

52.88

32.60

84

48.16

44.90

6.94

14.82

  1. N: Number of clones sequenced, Totals were calculated as the average of all values.
  2. p1: proportion of conserved codons as a percent
  3. p2: proportion of neutral codons as a percent
  4. p3: proportion of positively selected codons as a percent; dn/ds = dn/ds ratio at p3