Figure 5
IFN-γ T-cell responses against Tat, Rev, and Env after SIV infection. IFN-γ T-cell responses of the vaccinated animals were again measured by a IFN-γ ELISpot assay on PBMC from Days 28 and 42 post-infection. The activity levels against the peptide pools, Tat A, Tat B, Rev A, Rev B, Env A, and Env B, are shown for each animal in SFC per 106 PBMC at Day 74 (14 days prior to infection), Day 28 post-infection (p.i.), and Day 42 p.i. In most instances, the activity decreased significantly by Day 42 p.i. AV89's strong response against Rev (430 SFC/106 PBMC) was not shown, so that the y-axis maximum would be the same for each graph.