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Figure 4 | Retrovirology

Figure 4

From: Phosphatidylserine treatment relieves the block to retrovirus infection of cells expressing glycosylated virus receptors

Figure 4

Effects of PS concentration on cell-surface PS levels and RD114 vector infection of NIH 3T3 or NIH 3T3/ASCT2 cells. PS liposomes were generated and added to cells at concentrations of 0, 6.4, 32, 80, 240, 320, and 400 μM. Annexin-V staining and infections were undertaken as described in Materials and Methods. Top panel: Annexin-V staining of NIH 3T3 cells. Middle panel: RD114 vector [LAPSN(RD114)] infection of NIH 3T3/ASCT2 cells. Bottom panel: LAPSN(RD114) infection of NIH 3T3 cells. Data shown are the average of duplicates. The entire experiment was repeated twice with very similar results.

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