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Figure 2 | Retrovirology

Figure 2

From: Impact of amino acid substitutions in the V2 and C2 regions of human immunodeficiency virus type 1 CRF01_AE envelope glycoprotein gp120 on viral neutralization susceptibility to broadly neutralizing antibodies specific for the CD4 binding site

Figure 2

Comparison of the amino acid sequences between 2 AE-Env clones, 47PL1 and 47CC11. The deduced amino acid sequences of Env gp120 were compared between 2 AE-Env clones, 47PL1 [Genbank:EU743768] and 47CC11 [Genbank:EU743767]. The amino acid sequences were aligned using the ClustalW algorithm with slight manual adjustment. The positions of gp120 variable (V) and conserved (C) regions are denoted in the figure. Dots denote amino acid identity, while dashes represent gaps introduced to optimize alignment. PNLG sites are shown by underlining. The numbering of amino acid residues is based on the amino acid sequence of HXB2 Env and is shown beside the aligned sequences. Asterisks indicate the amino acid differences, a deletion, an insertion and an additional PNLG site found in the gp120 amino acid sequence of 47CC11 relative to that of 47PL1.

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Retrovirology

ISSN: 1742-4690

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