Table 1 Clinical and demographic characteristics of studied individuals
Discovery cohort | Replication cohort | |||
|---|---|---|---|---|
Characteristics | Patients | Controls | Patients | Controls |
Subjects (n) | 893 | 664 | 776 | 794 |
Female (n (%)) | 593 (66.4) | 371 (55.9) | 539 (69.5) | 513 (64.6) |
Age (years) (Mean ± SD) | 40.3 ± 9.5 | 41.2 ± 16.3 | 46.1 ± 11.4 | 40.2 ± 13.8 |
Age at onset (years) (Mean ± SD) | 28.6 ± 8.1 | - | 30.8 ± 9.7 | |
Clinical form: | ||||
RR (n (%)) | 595 (66.6) | - | 610 (78.6) | - |
SP (n (%)) | 51 (5.7) | - | 152 (19.6) | - |
PP (n (%)) | 64 (9) | - | 60 (7.7) | - |
Disease duration (years) (Mean ± SD) | 11 ± 6 | - | 13.2 ± 9.2 | - |
Current EDSS score (Mean ± SD) | 3 ± 2 | n.a* | ||