Figure 4

Association of rs6622139 with MSRV transcription levels in women (MS patients and controls). A) rs6622139*T allele (n = 136) was associated to a higher MSRV relative expression* than rs6622139*C allele (n = 22) (U-Mann–Whitney; p = 0.003). B) MSRV relative expression* according to rs6622139 genotypes (U-Mann–Whitney; CC (n = 3) vs. CT (n = 16): p = 0.03 and CC vs. TT (n = 60): p = 0.006). *MSRV Relative Expression = 2e-∆∆Ct = 2e-((Ct MSRV – Ct GUSB)_sample-Mean (Ct MSRV – Ct GUSB)_{Blood Donors}).