Table 1 Non-synonymous polymorphisms in the tetherin open reading frame
Allele count | ||||||
|---|---|---|---|---|---|---|
Amino acid change | rsID | European American | African American | All | Conservation (phastCons) | Clinical link |
Y8H | rs141648094 | G = 4/A = 8596 | G = 0/A = 4406 | G = 4/A = 13002 | 0.0 | Not known |
R19H | - | T = 2/C = 8598 | T = 0/C = 4406 | T = 2/C = 13004 | 0.0 | Not known |
N49S | rs144978205 | C = 6/T = 8594 | C = 0/T = 4406 | C = 6/T = 13000 | 0.591 | Not known |
D103N | - | T = 1/C = 8599 | T = 0/C = 4406 | T = 1/C = 13005 | 0.0010 | Not known |
E117A | - | G = 0/T = 8600 | G = 1/T = 4405 | G = 1/T = 13005 | 0.135 | Not known |
D129E | - | C = 0/G = 8600 | C = 2/G = 4404 | C = 2/G = 13004 | 0.0 | Not known |
V146L | - | A = 3/C = 8597 | A = 1/C = 4405 | A = 4/C = 13002 | 0.0 | Not known |