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Figure 3 | Retrovirology

Figure 3

From: A rare missense variant abrogates the signaling activity of tetherin/BST-2 without affecting its effect on virus release

Figure 3

Effect of variants on the ability of tetherin to restrict virion release. Virus release from 293T cells following transfection with a vpu-deficient proviral HIV-1 NL4-3 construct and varying amounts of plasmids expressing the indicated tetherin variants. Infectious virus yield was determined by infection of TZM-bl indicator cells and is shown as a percentage of that detected in the absence of tetherin (100%). Shown are average values ± SD derived from two independent experiments, each performed in triplicate.

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Retrovirology

ISSN: 1742-4690

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