Analysis of peripheral blood gut-homing α4+β7+T
populations. Subsets were defined on expression of CD28 within the CD95+ T cell population before and after infection under different conditions of replication permissivity. (a) Representative result illustrating the gating strategy. Comparison of frequencies of global, gut-homing, TCM and TEM CD4+ (b &c) and CD8+ (d &e) T cell populations before and after chronic SIV infection. Statistically significant differences are shown as ρ values determined by paired t-test.