Figure 9
PLAP incorporation causes mild reduction of viral entry activity in both mature and immature viruses. Different amounts of PLAP were incorporated in the immature (diamond) or mature (circle) HIV-1 particles bearing ΔCT Env. PLAP incorporation level was calculated as a PLAP:Gag ratio normalized to virus with 100% PLAP plasmid input. Specific entry activity indicates viral entry activity per Env, normalized to that of virus with no PLAP input. Error bars indicate the SEM.